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Jane's Blog Memory & Cognitive Decline Part 1

Posted by Jane Jansen on

Memory and cognitive decline is becoming an ever growing problem.

Watching a loved one slip away mentally and physically from Dementia / Alzheimer’s is so difficult.

Knowing that it could happen to you is terrifying!

Dementia is not a disease but a general term for loss of memory and other mental abilities severe enough to interfere with daily life. It is caused by physical changes in the brain. The causes of dementia can vary, depending on the types of brain changes that occur.

 It is not uncommon for people to have mixed dementia. For example, some people have both vascular dementia caused by narrowing of brain blood vessels from stiffening of the artery walls or plaque buildup and Alzheimer’s disease caused by amyloid plaques, tangled bundles of fibers called neurofibrillary, or tau, tangles and loss of connections between neurons in the brain.

Alzheimer’s disease accounts for 60 to 80 percent of dementia cases. Approximately 200,000 Americans under the age of 65 have early-onset Alzheimer’s disease. In its early stages, memory loss is mild, but with late-stage Alzheimer's, individuals lose the ability to carry on a conversation and respond to their environment.

The National Institute on Aging statesScientists are trying to discern the complex brain changes involved in the onset and progression of Alzheimer’s disease and it is likely that damage to the brain starts a decade or more before memory and other cognitive problems appear.”

Being proactive and taking care of your brain now, before it becomes too late to repair is imperative.

There are numerous supplements to help give nutrition to the brain and reverse some of the damaging effects of aging. However, if I had only one supplement to choose or start with, I would want Aged Garlic Extract because of its multiple benefits and numerous research studies.

First of all preventing and reversing plaque buildup in the arterial system of the brain can be a key factor to avoiding vascular dementia.

Over 700 studies have demonstrated that Kyolic Aged Garlic Extract (AGE) can protect against hardening of the coronary arteries by preventing a build-up of calcium inhibits the progression of coronary artery calcification.  In the January 2016 a study published in the Journal of Nutrition revealed Aged Garlic Extract can reverse the buildup of deadly plaque in arteries and help prevent the progression of heart disease and stroke.

A new understanding in neuroscience has established that alongside the amyloid plaques, neurofibrillary tangles and atrophy, neuro-inflammation plays a central role in the pathogenesis of Alzheimer’s disease, according to an article published in the September/October 2016 Progress in Neurology and Psychiatry.

Scientists have also discovered the immune response of releasing inflammatory mediators contribute to disease progression and severity of Alzheimer’s disease. It is hypothesized chronic inflammation occurs early in the disease and puts neurons in the brain under excessive stress.

In fact a study published in the February 2010 journal Neurology reports: “Neurodegeneration, the slow and progressive dysfunction and loss of neurons and axons in the central nervous system, is the primary pathological feature of acute and chronic neurodegenerative conditions such as Alzheimer’s disease and Parkinson’s disease.”

Now a new study published in the January 2017 journal NUTRIENTS  shows Aged Garlic Extract is protective of brain neurons by reducing neuro-inflammation.

A segment of the study states, “Over 350 scientific studies have shown that Aged Garlic Extract (AGE) is safe and effective in providing health benefits in humans. Its neuroprotective effect has also been evaluated in an animal model. AGE has the potential to protect the brain against neurodegenerative conditions by preventing brain injury following ischemia, protecting neuronal cells against apoptosis, and preventing Beta-amyloid-induced oxidative death.

Moreover, treatment with AGE or S-allyl cysteine has been shown to prevent the degeneration of the brain’s frontal lobe, improve learning and memory retention,and extend lifespan.”                                

The study goes on to suggest: “The results indicated that AGE at doses of 250 and 500 mg/kg BW significantly improved short-term recognition memory in cognitively impaired rats. In addition, AGE significantly minimized the inflammatory response by reducing the activation of microglia and IL-1Beta to the levels found in the control, which is similar to the results found in Celebrex-treated rats. In conclusion, AGE may be useful for improving the short-term recognition memory and relieve the neuroinflammation in ABeta-induced rats.”

(Study: Neuroprotective Effects of Aged Garlic Extract on Cognitive Dysfunction and Neuroinflammation Induced by Beta-Amyloid in Rats -The Journal Nutrients is an open access journal of human nutrition published monthly online by MDPI.)

Wakunaga of America-Kyolic is the only manufacturer of Aged Garlic Extract and have a wide variety of formulas including:

Kyolic® Brain Memory is a proprietary, triple-extract herbal blend containing a combination of Aged Garlic Extract, Ginseng Extract and Ginkgo Biloba Extract to support healthy brain function and memory.*

Kyolic® Brain Energy is a complete brain health formula containing a multi-nutrient blend of supportive herbs, vitamins and anti-oxidants for optimal brain performance.* Vitamin K1 enhances brain health and Folic Acid supports brain energy.* Aged Garlic Extract is a powerful antioxidant that can defend against oxidative stress and promote cognitive performance.* Cognizin® Citicoline is a patented, water soluble nutrient that improve brain performance and increase brain metabolism.* Bacopa is a Ayurvedic herb that supports improvement in learning, reaction time and cognitive function.* For more information go to     

As I stated above there are many nutrients beneficial for preserving your brain. So stay tuned for Memory and Cognitive Decline Part 2. Lots more to come!

Jane Jansen Practitioner Tree of Life Wellness Center

Host Holistic Healthline Radio


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