Gout is a type of inflammatory arthritis. It happens when the body makes excess uric acid, a normal waste product.
About two thirds of the uric acid in your blood is naturally made by your body. The rest is produced when your body breaks down substances called purines, which are found in many foods. High-purine foods include seafood, red meat, and alcohol.
Normally, your kidneys get rid of uric acid. But if they can’t properly flush it out, the uric acid accumulates and forms crystals in your joints. These uric acid crystals, called monosodium urate cause irritation, inflammation and swelling. This is known as a gout attack, which can be very painful.
There are several reasons why the blood may contain high levels of uric acid. It may be a result of the kidney's reduced ability to clear the uric acid. Insulin resistance/ metabolic syndrome has been shown to increase uric acid because the kidneys inability to clear it from the urine. It may be an overproduction of compounds known as purines. It may be a combination of both.
Normal blood levels of uric acid range between 3 to 7mg per deciliter (after fasting at least 4 hours)
Animal proteins are high in purine and raise uric acid levels associated with gout attacks.
Certain medications can increase uric acid levels in your body include: caffeine, aspirin, Cisplatin, diuretics, diazoxide, epinephrine, levodopa, ethambutol, methyldopa, niacin, theophylline and phenothiazines.
Diseases or some forms of medical conditions can also cause gout, including: hemoglobin disorders, congestive heart failure, leukemia, preeclampsia, high blood pressure, cancer, hypothyroidism, diabetes and lymphoma.
What you need to do to prevent or treat a gout attack!
1. Avoid foods high in purine: Meat: beef, pork, poultry, lamb, organ meats, seafood: particularly shellfish, anchovies, herring, as well as asparagus, spinach, beans, peas, lentils, oatmeal, cauliflower, and mushrooms
2. Alcoholic beverages: all kinds, particularly beer & wine.
3. Avoid high sugar foods, sweetened drinks, fruit juices, sweet fruits, and dried fruits as they increase inflammation and uric acid levels.
4. Eat more vegetables, nuts, seeds, as they contain apigenin and other flavonoids.
5. Drink lots of water to help flush the kidneys.
The enzyme xanthine oxidase is a catalyst for the oxidation of hypoxanthine to xanthine which then converts to uric acid. Apigenin is a potent inhibitor of xanthine oxidase. Apigenin is a flavonoid found in high amounts in parsley, thyme, and peppermint.
Quercitin also inhibit xanthine oxidase activity. Quercetin is found in the skins of apples and onions, most green vegetables, green tea, and a selection of dark-hued berries such as cherry fruit. The use of cherry extract has been associated with a 40% lower risk of recurrent gout flare-ups.
Curcumin is the most active chemical in the herb turmeric. It’s responsible for turmeric’s potent anti-inflammatory abilities. According to 2019 animal study in Arthritis Research and Therapy , curcumin can suppress a protein called nuclear factor-kappa B (NF-kappa B). NF-kappa B plays a major role in inflammatory conditions, including gout.
DMSO, or dimethyl sulfoxide, is a by-product of paper making. It comes from a substance found in wood. A study published in the March 31 2016 medical journal PLoS One found DMSO represses inflammatory cytokine production and reduces autoimmune arthritis. The researchers demonstrated topical administration of DMSO significantly mitigated K/BxN serum-induced arthritis in mice, and this was associated with reduced levels of pro-inflammatory cytokines in the joints and white blood cell levels in the blood. The FDA approved also DMSO for treating symptoms of painful bladder syndrome.
- N2Gout ( Vinco) to lower uric acid levels, contains Cherry fruit extract, Tumeric, Pantothenic acid
- Quercetin Bromelain
- Curcumin 500 mg 2 caps, 2 or 3 x day
- DMSO cream apply topically to decrease inflammation and break up crystal chards: Apply slight amount to affected joint as often as needed.
It is always best to consult with a practitioner particularly if you have complicated health concerns or are taking multiple medications. Telephone or in-office appointments are available at the Tree of Life Wellness Center call 508-336-4242 for more information.
Jane Jansen Holistic Practitioner Tree of Life Wellness Center Seekonk MA
Host of Holistic Healthline Radio
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